Shopping cart

Subtotal ₹0

View cartCheckout

  • +91 98288 92000
  • AlIMS Rd, Patrakar Colony, Shastri Nagar, Jodhpur, Rajasthan 342011
Make Appointment

PICSI Treatment Jodhpur

Select Smarter, Fertilize Better,
Succeed More

PICSI is an advanced sperm selection method that identifies physiologically mature sperm before ICSI using hyaluronic acid binding.

At Galwa Care Hospital, Jodhpur, PICSI is recommended selectively for high DNA fragmentation, recurrent loss or previous IVF/ICSI failure.

It helps choose sperm with better maturity and DNA potential, improving confidence during fertilisation planning.

Book IVF Free Consultation
Call Now

Are You Facing These Issues?

Free Consultation
from our Consultants

Biology Selects the Best Sperm for You

When and Why Is PICSI Needed?

PICSI is recommended in specific clinical situations where biological sperm maturity selection is expected
to meaningfully improve fertilization quality, embryo development, and overall treatment success.

High DNA Fragmentation in Sperm

When semen analysis reveals elevated levels of sperm DNA fragmentation, there is a higher risk of fertilization failure, poor embryo development, and recurrent pregnancy loss. PICSI helps select sperm with intact DNA, significantly lowering this risk.

Repeated IVF or ICSI Failures

Couples who have undergone multiple unsuccessful IVF or ICSI cycles without a clear explanation may benefit greatly from PICSI, as selecting physiologically mature sperm addresses hidden sperm quality issues that conventional visual selection cannot detect.

Recurrent Miscarriages

Recurrent pregnancy loss, particularly in the first trimester, may sometimes be linked to poor sperm DNA quality. PICSI ensures that only genetically sound sperm are used, potentially reducing miscarriage risk and improving the chances of a healthy full-term pregnancy.

Severe Male Factor Infertility

In cases of severe oligospermia, asthenospermia, or teratospermia, the available sperm pool may be limited and of variable quality. PICSI provides an additional biological layer of selection to identify the best available sperm even in the most challenging cases.

Poor Embryo Quality in Previous Cycles

If previous treatment cycles resulted in poor-quality embryos, arrested embryo development, or failed blastocyst formation, PICSI may be recommended to improve embryo quality and increase the likelihood of successful implantation.

Advanced Paternal Age

As men age, sperm DNA fragmentation tends to increase. For couples where the male partner is above the age of 40, PICSI can be a valuable tool in ensuring the best quality sperm are selected to optimize the chances of a healthy pregnancy.

Biologically Guided, Precisely Executed

The PICSI Procedure

PICSI follows the standard IVF and ICSI workflow with the addition of a specialized hyaluronic acid binding step that selects only the most biologically mature and.

Ovarian Stimulation and Egg Retrieval

The female partner undergoes controlled ovarian stimulation using hormone injections to develop multiple mature eggs, which are then retrieved through a minimally invasive ultrasound-guided procedure under light sedation.

Semen Collection and Preparation

Required preparation, screening and safety checks are completed before sample collection or procedure planning.

PICSI Dish Preparation

Required preparation, screening and safety checks are completed before sample collection or procedure planning.

Physiological Sperm Binding

Sperm are incubated with the hyaluronic acid droplets for a defined period. Only biologically mature sperm with low DNA fragmentation, intact acrosome function, and proper nuclear configuration.

Sperm Selection

Bound sperm that have demonstrated physiological maturity through the HA binding process are identified and carefully selected by our embryologist for use in the subsequent ICSI microinjection step.

Microinjection (ICSI)

Selected sperm is injected into mature eggs under high-precision laboratory conditions to support fertilisation.

Embryo Culture and Development

Embryos are cultured and monitored for development, quality and suitability before transfer or freezing.

Embryo Transfer and Pregnancy Test

The selected embryo is placed gently into the uterus with careful timing and ultrasound-guided precision.

Biology and Science Working Together

Benefits of PICSI Treatment

PICSI improves sperm selection by identifying biologically mature sperm with better fertilisation potential.

Superior Biological Sperm Selection

PICSI selects sperm based on biological maturity and DNA integrity rather than appearance alone, resulting in a more informed and scientifically robust fertilization process.

Reduced DNA Fragmentation

By filtering out sperm with damaged or fragmented DNA through the HA binding process, PICSI lowers the risk of genetic abnormalities being carried into the resulting embryo.

Improved Fertilization Rates

Physiologically selected and biologically mature sperm have a meaningfully better chance of successfully fertilizing the egg, supporting higher and more reliable fertilization rates.

Better Embryo Quality

Embryos formed from HA-bound sperm tend to be of higher quality, demonstrating improved cell division, stronger developmental grading, and better blastocyst formation potential.

Reduced Miscarriage Risk

Better quality embryos resulting from PICSI selection are more likely to implant successfully in the uterine wall, improving the overall success rate of each IVF transfer cycle.

Reduced Miscarriage Risk

Using sperm with intact and undamaged DNA significantly lowers the likelihood of early pregnancy loss associated with chromosomal or genetic anomalies in the embryo.

No Additional Patient Intervention

PICSI adds no additional physical procedure or discomfort for the patient. It is an enhanced laboratory process carried out entirely during standard IVF and ICSI treatment.

Cost-Effective Over Multiple Cycles

Improved success rates per cycle reduce the total number of treatment cycles many patients need, making PICSI a sound and cost-effective investment for carefully selected patients.

Clinically Validated and Safe

PICSI is a well-established, clinically validated technique with an excellent safety profile supported by international research and peer-reviewed studies in reproductive medicine.

Emotionally Reassuring for Couples

Knowing that the most scientifically robust biological sperm selection method has been applied provides couples with greater confidence and meaningful peace of mind throughout their fertility journey.

Protect Sperm Quality, Support Your Cycle

PICSI Treatment — Do's and Don'ts

Following these recommendations throughout your PICSI treatment cycle will protect sperm DNA integrity, support egg quality, and give your biological sperm selection process the best possible foundation.

DO'S — What You Should Do

Take all prescribed fertility medications on time and at the correct dosages.

Attend every scheduled ultrasound and monitoring appointment without fail.

Maintain a nutritious diet rich in antioxidants, lean protein, and vitamins.

Stay adequately hydrated throughout the stimulation and treatment phase.

Take prescribed prenatal vitamins including folic acid, zinc, and omega-3.

Follow all post-transfer rest and care instructions carefully as provided.

Communicate openly about any questions or concerns with your fertility team.

Practice stress management through gentle exercise or mindfulness meditation.

Continue all prescribed progesterone medications consistently during the wait.

Attend the pregnancy test and all follow-up appointments as scheduled.

DONT'S — What You Should Avoid

Do not skip or adjust medications without consulting your specialist first.

Avoid smoking as it significantly reduces sperm DNA quality and IVF success.

Do not consume alcohol during the cycle as it impairs embryo development.

Avoid intense physical exercise and heavy lifting after retrieval and transfer.

Do not use hot tubs or saunas as heat exposure damages sperm quality.

Avoid taking unprescribed supplements or herbal products without approval.

Do not consume excessive caffeine, keep to one small cup per day maximum.

Avoid processed foods and trans fats as they impair egg and embryo quality.

Do not take a pregnancy test before 14 days post-transfer as results mislead.

Do not lose hope after one cycle, discuss protocol adjustments with your specialist.

World-Class Fertility, Right Here in Jodhpur

The Right Sperm, Selected the Right Way

Expert fertility team with advanced training in PICSI and all modern ART procedures

State-of-the-art IVF laboratory featuring PICSI dishes and micromanipulation systems

High success rates underpinned by rigorous quality control and evidence-based protocols

Personalized treatment plans built around each patient's unique clinical profile

Transparent communication ensuring every patient is fully informed at each step

Compassionate, patient-first approach with dedicated counselling throughout the journey

Affordable, transparent pricing with flexible payment options for all fertility services

2000+

Eggs Successfully Frozen

98%

Vitrification Survival Rate

15+

Years of Experience

24/7

Support to Call

Advanced Selection, Clear and Fair Pricing

How Much Does PICSI Treatment Cost?

PICSI is offered as a specialized sperm selection add-on to a standard IVF and ICSI cycle. Its cost is incorporated into the overall treatment plan and communicated clearly and transparently at Galwa Care Hospital with no hidden charges at any stage.

Easy EMI Facility Available

Ovarian stimulation medications

Monitoring scans and blood tests

Egg retrieval procedure

PICSI dish and HA binding test

ICSI microinjection procedure

Embryo culture and grading

Embryo transfer and luteal support

Easy EMI Facility Available

Shape Image

PICSI Questions Clearly Answered

Frequently AskednQuestions.

PICSI (Physiological Intracytoplasmic Sperm Injection) is an advanced sperm selection technique that uses a hyaluronic acid (HA) binding test to identify and select biologically mature sperm before fertilization. Hyaluronic acid is a naturally occurring substance found on the surface of mature eggs. In nature, only sperm with complete DNA and low genetic fragmentation can bind to it. The PICSI dish replicates this environment, and only sperm that successfully bind to the HA droplets, demonstrating true physiological maturity, are selected for injection into the egg.

In standard ICSI, sperm are selected based purely on visual appearance and motility under a microscope. PICSI adds a biological layer of selection using the hyaluronic acid binding test, identifying sperm based on their functional maturity and DNA integrity rather than appearance alone. IMSI uses ultra-high magnification to assess sperm morphology visually in far greater detail than standard ICSI. PICSI and IMSI address different aspects of sperm quality and can sometimes be used together for the most comprehensive sperm selection approach available.

PICSI is particularly recommended for couples with high sperm DNA fragmentation, repeated IVF or ICSI failures, recurrent miscarriages, poor embryo quality in previous cycles, or advanced paternal age where DNA fragmentation is more likely to be elevated. Clinical studies indicate that PICSI can improve fertilization rates, embryo quality, and implantation success in these specific patient groups. However, like all fertility treatments, PICSI does not guarantee pregnancy. Results vary between individuals and your specialist at Galwa Care Hospital will provide a realistic and honest assessment of expected outcomes.

Not at all. PICSI is entirely a laboratory-based process and involves no additional procedures, discomfort, or physical intervention for the patient beyond a standard IVF and ICSI cycle. The hyaluronic acid binding step typically takes 15 to 30 minutes and is carried out on the same day as egg retrieval and fertilization, adding no significant time to the overall treatment process. PICSI has an excellent safety profile and does not introduce any additional clinical risk to the egg, embryo, or patient at any stage.

Yes, in many cases. Even when sperm count is very low, PICSI helps identify the most biologically sound and mature sperm available within the limited sample, maximizing the quality of the fertilization outcome from whatever sperm are present. Frozen sperm that has been thawed and prepared in the laboratory can also be used effectively in PICSI, as the hyaluronic acid binding process works equally well with prepared thawed samples. Your specialist at Galwa Care Hospital will assess suitability based on your individual semen analysis results.

Appointment Request Form

Infertility
Gynaecology
IVF
Plastic Surgery
Cosmetic & Hair Transplant
Cosmetic Gynaecology
Pregnancy Care
Health Screening

Care Packages for Every Stage

  • Fertility & IVF guidance
  • Women’s wellness care
  • Aesthetic consultation
Explore Packages
Talk to Care Team

Take the First Step Towards Better Care

Schedule your personalized consultation at Galwa Care Hospital to experience medical expertise combined with compassionate support for every patient journey
+91 98 288 92000
GALWA CARE